The British Pharmacopoeia Commission has caused this British Pharmacopoeia 2016 to be prepared under regulation 317 (1) of the Human Medicines Regulations 2012 and, in accordance with regulation 317 (4), the Ministers have arranged for it to be published. It has been notified in draft to the European Commission in accordance with Directive 98/34/EEC. The monographs of the Eighth Edition of the European Pharmacopoeia (2013), as amended by Supplement 8.1 to 8.5, published by the Council of Europe are reproduced either in this edition of the British Pharmacopoeia or in the associated edition of the British Pharmacopoeia (Veterinary).